Friday 10 April 2015

Episode 23: 64 days on MiniMed 640G System: The Wrap - Managing My Type 1 Diabetes

Welcome to my final VLOG!

This is the wrap and is based on three things:

1. Comparing the 64 days on the MiniMed 640G (Feb to April 2015) with 64 days on the VEO from (October to December 2014 ) In terms of; HbA1c, number of hypos, alarms, time managing diabetes

2. A summary of The Good, The Bad & The Ugly of the MiniMed 640G and how to manage expectations. Plus a surprise about the #DOC

3. Final bit of frivolity and stupidity by me!



For those finding this VLOG for the first time you can see on the history bar on the right hand side a chronological list of the VLOGS to find more info on:

1. Why doing this 64 days - episode 1
2. The MiniMed 640G, how to set up, the features etc - episodes 2 - 8
3. What is CGM, SmartGuard, Setting for SmartGuard - episodes 5-8
4. First two weeks and SmartGuard in action - episodes 9 - 18
5. Adapting SmartGuard settings for day, night and post-meals - episode 18
6. 7 top tips to get best Enlite Performance, mine improved from 13% MARD to 10% - episode 16
7. How Alcohol interacts with diabetes and managing a stag do and recovery - episodes 17, 19 - 20
8. How exercise changes glucose levels and how you can manage - episodes 21 - 22
9. See more on the MM640G at:

Comparing 64 days on MiniMed 640G with VEO:

Important point to note that 3 hypos per week is normal for people with type 1 diabetes achieving good control HbA1c <7.5% (58mmom/mol). People having 0 hypos per week are invariably running their blood glucose high due to fear of hypos or because they plain don't like them and they have 4+ hypos per week when try to run tight control. This is the paradox of diabetes management hypos are inevitable if you are going to run tight control, the trick to try to minimise them!

  VEO  64 days MM640G 64 days
Weight (kg) 95kg 95kg
BG number in 64 days 554 495
BG Average per day 8.6 7.8
BG Average (mmol/l) 7.1 7.1
BG Standard deviation (mmol/l) 2.8 2.7
AUC <3.5 0.03 0.01
AUC <9.0 0.19 0.36
SG Average (mmol/l) 8.3 7.3
SG SD (mmol/l) 2.1 2.3
Average carbs  326 295
Insulin units Average 36.3 35.3
Basal % 40% 37
Bolus % 60% 63%
U/kg 0.38 0.36
Clinical Measurements    
HbA1c % 6.1 5.8
HbA1c (mmol.mol) 43.0 40.0
Hypos <3.5mmol/l in 64 days 30 28
Hypos <3.0 in 64 days 15 14
high alarms per day 0.8 0.9
Low alarms per day 11.8 0.8
Suspends duaration per day (hrs min) 0 mins 2hrs 8 min per day
Number of suspends per day 0 2.1


The table shows clearly the same clinical results can be obtained form the VEO when compared with the MiniMed 640G, however, what the table also clearly shows is that to obtain the same results I had to respond to the VEO low alarms 12 times per day which means:

  •  90-120 minutes per day managing low alarms with extra carbs, temp basals and increased surveillance. 10 -15 extra hours per week!

  •  8 hours lost sleep managing low alarms
The two graphs below show the significant reduction in nocturnal hypoglycaemia (hypos during the night) achieved by SmatGuard. Graph 1 shows the three month sensor overlay from the VEO where the concentration of the red (hypo) is overnight and this meant lots of alarms, biscuits and lost sleep.
Graph 2 backs up what I have been saying in the VLOG that SmartGuard works at its best overnight when there is only basal insulin causing hypos! A massive difference being full nights sleep and hardly any biscuits during the night (keeping my waistline in check!)

Graph 1: VEO three month sensor overlay
    Graph 2: MM640G three month sensor overlay

Amazing results can be achieved with the Veo and Real-time CGM BUT not many people, are prepared to do this because:
  • They have lives outside of Diabetes
  • They have not been taught the skills and solutions on how to manage the alarms well
  • It's a hell of a lot of work
  • They are not a diabetes nerd like me!

The MiniMed 640G allowed me to have the same control with only 1 low alarm per day due the Smart Guard protection from hypos and safety, which meant I got 10-12 hours per week back, 8 hours more sleep and a significantly lower risk of diabetes burn out!

This was achieved by the MiniMed 640G suspending and re-starting the basal on average 2.1 times per day for a total of 2hrs 8minutes (Smart Guard) without any alarms! The crazy thing is looking back at my download there was no patterns to say I needed to reduce basal at a certain time of day or change carb ratio. It was just natural daily variation of activity, food intake and mood that meant Smart Guard has become invaluable in keeping good control, preventing hypos and keeping my sanity! I think people with diabetes and Clinicians alike will have to learn two suspends per day is completely normal and healthy if good control and low number of hypos is going to be achieved!

I am prepared to manage all the alarms with the VEO but a for a lot of people with diabetes the alarm fatigue is too much (the same for any CGM system be it Dexcom, Animas Vibe, Abbott Navigator). Its my opinion that this is the first real step towards the closed loop allowing semi-automation of hypo management and will mean more people will be able to manage CGM without diabetes burn out! but this in only my opinion!

I know for me I think much less about my diabetes and more about living life!

If you want the download pdf's email me at jspfree2@gmail.com  and I will send them. This BLOG will not allow me to upload PDF's. Key pages are at the bottom of this BLOG

MiniMed 640G: The Good, The Bad and the Ugly

As a stand alone pump it has almost everything you would want. The Good
  • Very easy to use, navigate and easy to follow instructions
  • Waterproof
  • Colour screen that's adjusts to light
  • Alternate basal profiles
  • Remote bolus with also pre-set bolus option
  • Sex appeal, no longer a an 80's pager, but now a 90's IPOD!
  • The safest Bolus Wizard technology that takes into account both bolus and correction insulin for active insulin (IOB, BOB) for safety, unlike some other pumps that only take into account correction insulin.

The bad:
  • No bolus wizard in remote bolus
  • Change sensor alarms - listen to VLOG for full explanation
  • Still has a tube, however due to the recently published accuracy difference between tubed (95% accurate) and patch pumps (66% accurate), I will take a tube pump any day!
    • J Diabetes Sci Technol 2013;7(4):1011–1020
The Ugly:
  • Me in the shower showing the waterproof off!

One thing to consider when choosing a pump is do you think you may use or need CGM as an option in the next 4 years due to:
  • Issues with hypos like me
  • Funding becomes more readily available by the NHS or your funding provider, country dependent (there are international viewers don't you know! Ha)
  • The companies make the sensors cheaper and therefore more affordable for self-funders
  • You become pregnant and need very tight control
  • You have erratic control due to hectic lifestyle
If the answer to any of the above is yes it would be advisable to choose a pump with CGM capability and as I have discussed above in my opinion the MiniMed 640G is the first real step towards closing the loop. There are lots of good CGM systems out there (Dexcom, Abbott Navigator, Animas Vibe) which work very well and by reading lots of BLOGS and VLOGS it seems with the Dexcom Sensor, you can get extra sensor life which is great for self-funders but you have to be prepared for the alarms and extra 10-15 hours per week managing and some sleepless nights. If like me you would prefer to have semi-automation the MiniMed 640G would be my choice but everyone has different priorities and as the NHS funds my CGM due to previous severe hypoglycaemia, it's hard for me to be fully balanced n this point. Oh and did I mention I work for Medtronic, well maybe once or twice!


Its a wrap

I have a new found love for the #DOC (Diabetes Online Community for the internet virgins, which was me until 64 days ago!) who are a very knowledgeable and helpful bunch of ego maniacs (me included), gentle helpful soles and philosophers! Peer support from PWD (People With Diabetes, everyone loves an acronym, especially the NHS) is key with diabetes and I know believe online really offers this!

Technology is great but by far the most important aspect of diabetes management is the person/families education, knowledge, management strategies, positive attitude towards a condition that does not let you have a day off from constant blood glucose checks, planning, review and modification. My strongest advice is to educated your self by:

  1. Attending a structured education programme such as DAFNE or local equivalent.
  2. Read key books by great diabetes authors such as:
    1. Gary Schiener - Think like a pancreas
    2. John Walsh - Pumping insulin or Using Insulin
  3. Get good at carb counting - even as a Registered Dietitian I still have a lot to learn (Thanks Andy Sherwood @colonelblighty) that's why I love the #DOC
  4. Adhere to the 7 P's: Prior Planning and Preparation Prevents Piss Poor Performance
    1. My Uni Lecturer Dr. Ian Kenvyn taught me that and it invaluable
    2. Myself and best mate Phil Hayes CEO of Kloodle follow this religiously
  5. Finally the 3 P's, diabetes is a life long fight that never gives an inch but by realising you cannot win every battle but you can win the war, you can prevail:
    1. Positive
    2. People
    3. Prevail



Thanks for watching! over 10,000 page views since I started and I have hopefully educated, entertained and for sure made you cringe!

I may do some VLOG's after the cricket season on carb counting and other aspects of diabetes management. If you would like me to do some more let me know in the comments below or at @MM640G


Thanks again for viewing


AND CUT (Martha, stole your line!)

Cheers

John

See the download pics below first from the MM640G and then the VEO. What amazed me was the reduction in time spent hypo overnight!

Download pics from MiniMed 640G
 (1. sensor overview 2. meter bg over view 3. day by day - See the blue snippets of basal suspend to view the frequency and help of SMART GUARD)



Download pics from VEO
 (1. sensor overview 2. meter bg over view 3. day by day)





Wednesday 1 April 2015

Episode 22: 64 days on MiniMed 640G System: Exercise week - Managing My Type 1 Diabetes

Welcome back!

This VLOG is an exercise frenzy showing the effect of exercise in Diabetes Control. Key aspects being the difference between:
1. Exercising with active insulin board and not
2. Endurance exercise vs. Resistance exercise
3. Planning for before, during and after exercise

Other Highlights include:
1. Seeing Danielle's Yoga Moves
2. Seeing Becky and Lucy take on the old man (me) at Functional Fitness
3. Me overdosing on chocolate before exercise - Nightmare

To get the full exercise story please see:
1. Episode 21 for the full explanation of diabetes and exercise and planning

2. Episode 14 for resistance exercise and diabetes



An example of the Yoga that was missing!



Excellent Web-Sites that have really good Exercise and Diabetes information:
Excarbs - By Diabetes and Exercise Gurus: David Kerr, Helen Partridge, Michale Riddell
Diabetes Motion - Sheri Colberg - leading Diabetes and Exercise Expert


A good recent blog done by Dave Sowerby - http://www.thetangerinediabetic.blogspot.co.uk/

A Massive thanks the Sam Smith, owner of RIGS FITNESS for allowing me to film some of the sessions and generally owning the best gym! Check it out at the below sites

RIGS FITNESS: https://www.facebook.com/ElitePerformanceCentre?fref=ts
RIGS FITNESS Videos: https://www.facebook.com/ElitePerformanceCentre/app_212104595551052


Massive Thanks to Danielle for being a wicked Yoga Instructor.


Danielle Yoga Instructor: https://m.youtube.com/watch?feature=youtu.be&v=2ZSOoqo8N0s

 
Thanks to Becky and Lucy for being great sports and all round future fitness superstars!



Becky Hayes: https://instagram.com/beckyhayes1992/   Twitter: https://twitter.com/beckylhayes
Lucy Turnbull: https://instagram.com/lucyturnbull1/    Twitter https://twitter.com/LucyTurnbull1


Well I hope this helps and also provides a little inspiration that with a little planning people with type 1 diabetes can do whatever they want! Well apart from overdosing on chocolate!

Trying to make a decision on the next VLOG, options are:
1. Carb counting
2. Sensor performance, expectations and how MARD gets better after day one of insertion, false suspends and how to manage
3. Review of SMART GUARD and where works its best and where it does not
4. Open to ideas if you want something specific

Let me know what you would prefer by comment below or on Twitter @MM640G

Until next time! Oh and don't overdose on Chocolate! It's only Easter after all1

John

Episode 21: 64 days on MiniMed 640G System: 24 hours Charity Cycle - Managing My Type 1 Diabetes

Hello and welcome back,

Please find below my VLOG all about the 24 hour Charity Bike Ride I took part in on the 20th to 21st of March.




Highlights for diabetes management include:
1. What happens in the body during exercise and what are the risks for people with type 1 diabetes
2. How I plan my exercise management to prevent hypos
3. CareLink analysis of how my plan worked

Highlights for fun and charity:
1. we have raised 3,000 for Bury Hospice, if you would to donate please go to:
2. See the article in the Bury Times: http://www.burytimes.co.uk/news/12585368.Cricketers_cycle_the_equivalent_distance_of_Bury_to_Russia_during_24_hour_charity_ride/?ref=twtrec

3. See me in a pink leotard and Rio Parrott suit whilst cycling
4. See my mate Jamie's Rock dance to Jimmy Eats World "In the Middle"
5. See mine a Phil's battle to see who can cycle the furthest
6. See a preview of next weeks exercise VLOG that includes the lovely ladies below:

Becky Hayes: https://instagram.com/beckyhayes1992/   Twitter: https://twitter.com/beckylhayes
Lucy Turnbull: https://instagram.com/lucyturnbull1/    Twitter https://twitter.com/LucyTurnbull1


Danielle Yoga Instructor at RIGS FITNESS:
Danielle in action:
RIGS FITNESS: https://www.facebook.com/ElitePerformanceCentre?fref=ts
RIGS FITNESS Videos: https://www.facebook.com/ElitePerformanceCentre/app_212104595551052


 
 
Well thanks for watching and reading and I look forward to sharing my exercise VLOG next week!
 

 
All in aid of great cause!
 
Out for now
 
John

Thursday 26 March 2015

Episode 20: 64 days on MiniMed 640G System: Stag do Recovery! - Managing My Type 1 Diabetes

Hey ya,

See below my VLOG on the aftermath of the Stag Do! Wow, fair to say a lot of fun but the pain came hard on return.

See how the MiniMed 604G and SmartGuard performed in Prague!

 


Next VLOG's are:

1. 24 hours Charity Cyle to raise money for Bury Hospice: Stupid costumes, exercise and diabetes management and dance party afterwards!

2. Managing different types of activity: Yoga (new teacher Danielle!), Circuit classes, Cricket training, running and weights

Hope you find it useful

Oh and did I mention I work for Medtronic! (ha!)

Saturday 7 March 2015

Episode 19: 64 days on MiniMed 640G System: Week 3 Stag Do Practice - Managing My Type 1 Diabetes

Welcome to my third week on the MiniMed 640G System. The video talks through a little about my third week but focusses on the preparation I have been undertaking for my mates Stag Do in Prague next weekend!


I have summarised what the video discusses below:

New Orange Rubber Skin

My favourite part of this week has been getting my new Orange Rubber Skin.  At the age of 34 I thought I had grown out of things like this! Evidently not!

 
 



I have given my spare purple one to Dave Sowerby for his MM640G, mainly because of his lovely daughter Martha requested it, check her filming master pieces of “And Cut”! still makes me giggle. The Rubber Skins can be purchased on the web shop but as I work for Medtronic I shall see what my I can find at head office this Tuesday just lying about! I may have one for Ninjabetic at DUK next week

SmartGuard continues to rock!
I sound like a broken record and am even boring myself but SmartGuard continues to prevent 2-3 hypos per day independently without alarming at me! It has given me two hours per day of life back that I previously spent managing CGM alarms and hypos. Now I get a full night’s sleep for the first time in a long time, which is to quote MasterCard #priceless, well not really as CGM does cost! Here is an example where SmartGuard kicked in twice (orange shaded area) to prevent hypos during the day. Only knew when I reviewed just at tea time, no alarms! I Love you SmartGuard!
 

This seems to be the experience of two other VLOGGERS Laura and Dave, so please have a look to compare and contrast as I you may think I have a slight bias as I work for Medtronic! Also there is another blog here of one blogger who is having a few issues, always get a balanced view!

Laura “Ninjabetic” Cleverly @ninjabetic1 Blog YouTube

Dave “Tangerine Diabetic” Sowerby  @SowerBee Blog

Little D – Blog

Previous videos to help about SmartGuard: Simple how SmartGuard works; Detailed how Smart guard works
 
Practice for Prauge
I am going to Prague next weekend for three days of drinking, partying and generally all things unhealthy and potentially dangerous for people with type 1 diabetes. I am not about to let Type 1 Diabetes get in the way of me giving my good mate a fantastic send off!  This does however require a good plan and practice! I have been practicing this for the last 10 years fairly frequently so I feel in a confident position J . With my new house mate moving in last Friday one final practice run was in order on the Saturday night!
 
I have previously discussed and shown via red wine experiment the effect of alcohol on Blood glucose levels and that the major concern is delayed hypoglycaemia. I choose to drink alcoholic drinks with no carbs so I can manage more easily by only having to reduce the basal insulin, rather than having to give insulin initially for carb content in drinks such as beer and cider and then have to worry about going low after! Experience has taught me this is an art form I have not mastered, especially when a good night is in progress managing diabetes goes out of the window!


So in earnest Phil (new house mate) and I hit the town. Before I did here was my plan:

1.       Set a basal profile 2 with 25% less insulin on all basal – using new MM640G Copy basal function is really easy (see 3min 15 seconds to 4 minutes)

2.       Set Bolus Wizard target to 7.0 – 7.0 so only correct to 7.0, usually 5.2-5.2

3.       Change sensitivity from 3.0 to 6.0 so corrections made 50% weaker and confidence to correct if needed

4.       Get on my party shoes and limber up for some dancing!!!!

You can see from the screen shot here that my plan worked perfectly through the night out, finished at 3.30am! But as the delayed effect of alcohol (20 units alcohol from 2 bottles of wine, also 4 Sambuca’s = 4 units, therefore liver processing alcohol and reducing glucose output processing from 20:00hrs to 20:00hrs the next day!) took hold my glucose started to drop and was heading towards hypo and at 07:00 and SmartGuard kicked in to prevent this and allowed me to sleep in till 09:30 when Tinkerbelle (my Cat for those with a dirty mind!) woke me wanting breakfast! What I did not cater for was that I bloused full insulin for breakfast at 09:30 and SmartGuard had to kick in and save my ass again at 11:00! There is a learning here!  So overall SmartGuard was very useful here but I now have further developed my plan for Prague!


 
My final Plan for Prague:

1.       Basal Profiles:

a.       Set a basal profile 2 with 25% less insulin on all basals –for day 1

b.      Set basal profile 3 with 35% less insulin on all basals – for day 2

c.       Set basal profile 4 with 45% less insulin on all basals – for day 3

 

2.       Increase the SmartGuard low limit to 4.0 for the stag do so the suspend before low and dynamic basal resume to aim to keep my level above 5.1 (1.1 above low limit)

 
3.       Set Bolus Wizard target to 7.0 – 7.0 so only correct to 7.0, usually 5.2-5.2


4.       Change sensitivity from 3.0 to 6.0 so corrections made 50% weaker and confidence to correct if needed

 
5.       Change carb ratio from 15 to 22 (25% less insulin) – to prevent the problem of last Sunday morning!
 

6.       Set a Pre-set bolus of 0.5 units for each pint of beer so I can remote bolus from the Contour Next Link 2.4 meter. I do not normally drinks alcoholic drinks with carbs in but I can see this happening


7.       Pack my orange rubber skin, dancing shoes, Paracetamol for headache from party trick of headstand (below) and camera for VLOG and so I do actually have memories!

 
8.       Pack lots of dextrose, have ID bracelet on and a good mate of mine is trained and carries Glucagon. This is not normal procedure for a night out but this is essentially a three day bender where the 7 P’s must be applies: Prior Planning & Preparation Prevents Piss Poor Performance!

 


 
Well hope you enjoyed it! Feel free to comment and ask questions here or @MM640G
 

I will do a foggy VLOGGY next week when I have returned, if I do!


Disclaimer: I am not suggesting anyone follow this advice and it is certainly above the government recommendations of 3-4 units of alcohol per day. However it is real-life and the real-life experience of someone who has type 1 diabetes who has found a way!

Friday 27 February 2015

Episode 18: 64 Days on MiniMed 640G: Managing my type 1 diabetes: Week 2 SmartGuard kicking hypos Ass!


Welcome to the 2 week review of my 64 days experience of MiniMed 640G with SmartGuard.

 

See the video for full details but the highlights are here:

 

1.      SmartGuard prevented 2-3 hypos independently with no alarms! Lots of overnight hypos avoided! Another week of full sleep boom, see the three overnight examples!

 
 
 

 

2.       Smart guard prevented nocturnal  hypo after drinking wine see: http://www.mm640g.blogspot.co.uk/2015/02/smartguard-works-with-red-wine-check.html

 

3.      Enlite accuracy improved from 15% in week 1 to 11% in week 2 following the 7 top tips: with 80% spent in target of 3.5 – 9.0mmol/l: http://www.mm640g.blogspot.co.uk/2015/02/improve-enlite-accuracy-7-tops-tips.html

 

 

4.       SmartGuard works at its best:

a.       Overnight when only basal insulin in play causing hypos and no rebound hypers!

b.      2hrs post meal when bolus insulin is diminishing

 

5.      SmartGuard could not prevent hypos when over bloused in two hours post bolus.
 
 
6. When SmartGuard has worked a couple of times pre-meal there maybe a risk of post-meal highs. See the first graph when pre-lunch there has been very little suspend so a good amount of basal present pre-lunch bolus and no post-meal rise. The second graph shows two suspends pre lunch (great as hypo avoided) but  very little basal pre-lunch bolus and consequent post-meal rise. Therefore at meals when I look back and see the orange shaded area pre-meal I will add a bit extra onto the bolus!
 
 
 
 

 

6.       Change of SmartGuard setting required - See my shady diagram!

a.       Overnight set at 3.0 so MiniMed 640G will prevent going lower than 4.1 (1.1. above) – alarms off

b.      Two hours post-meal set at 3.4 (keep above 4.5) – alarms on to warm as may need extra carbs

c.       After two hours post meal back to 3.2 (keep above 4.3) – alarms off



7.       VLOGS to come:

a.       Carb counting and fibre using European labelling not US!

b.      Sensor accuracy explained – WTF is MARD?

c.       My top tips for getting Better Control
 
Enjoy your weekends!

 

Tuesday 24 February 2015

Episode 17: 64 Days on MiniMed 640G: Managing my type 1 diabetes: SmartGuard works with Red Wine? Check! Foggy head? Check! All in thename of Type 1 research debateable!

I thought I would put Smart Guard to the test with a little red wine tipple on a Tuesday evening, which seemed like a good idea at the time but now it's Wednesday morning and the red wine fog has emerged, I am not so sure!

I have just inserted my third sensor and this picture shows after inserting the new sensor it was tracking well. The first only lasted four days but the second sensor the full six days. Lets see how the third one goes.
 
The theory with alcohol is that each unit of alcohol takes 1 hour to be processed by your liver (detoxify the poison). Whilst the liver is detoxifying the alcohol it significantly reduces its output of glucose, the main reason why we have basal insulin. So in theory if the BG is stable before bed, your have some alcohol with no carbs and do not reduce your insulin (in my case the basal rate) you should have a hypo! So I decided half a bottle of red wine (5 units of alcohol with very little carb content) whilst watching the cricket world cup would be a good idea to see if Smart Guard stopping and restarting the basal would work!
 
 
This picture shows the morning calibration was pretty spot on with the sensor and looking back on the last three hours there had been no Smart Guard action. All I have to show for my troubles is a red wine fog!!!!
 
 
 
However on second look back over the night your can see here you can see between 01:30 - 02:15 there was a suspend before low and automatic basal resume preventing a hypo. As I had the wine at 22:00 I would have expected the liver to be producing little glucose from 10:00 to 03:00 (5 units of alcohol takes 5 hours to be processed), therefore a Smart Guard event at 01:30 is right where you would expect it to work. Sweet I do not need to worry about recovering from a hypo this morning BUT Smart Guard unfortunaltey does nothing for the hangover! URGH
 
 
It seems Smart Guard will help with a little mid week tipple! The bigger challenge will be the upcoming stag do to Prague! Anyone got any experience and suggestions.
 
Well the good thing is the alcohol will have been full processed by 03:00 so ready to drive for work, just hope these Paracetamol kick in quick time!